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Cannabis ‘could stop dementia in its tracks’

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Cannabis ‘could stop dementia in its tracks’

By Fiona Macrae

11/19/11: Cannabis may help keep Alzheimer’s disease at bay.

In experiments, a marijuana-based medicine triggered the formation of new brain cells and cut inflammation linked to dementia.

The researchers say that using the information to create a pill suitable for people could help prevent or delay the onset of Alzheimer’s.

A medicine based on cannabis (right) could help to delay the onset of Alzheimer’s

The incurable disease affects 400,000 Britons, with around 500 new cases diagnosed every day as people live longer.

For some sufferers, drugs can delay the progress of devastating symptoms such as memory loss and the erosion of ability to do everyday things such as washing.

However, there they do not work for everyone and, with the number of patients forecast to double in a generation, there is a desperate need for new treatments.

The US researchers studied the properties of a man-made drug based on THC, the chemical behind the ‘high’ of cannabis.

When elderly rats were given the drug for three weeks, it improved their memory, making it easier for them to find their way round a water maze, the Society for Neuroscience’s annual conference heard yesterday (WEDS).

Researcher Dr Yannick Marchalant said; ‘Old rats are not very good at that task.  When we gave them the drug, it made them a little better at that task.’

Other experiments showed that the drug acts on parts of the brain involved in memory, appetite, pain and mood.

The Ohio State University experiments also showed that the drug cut inflammation in the brain and may trigger the production of new neurons or brain cells.

Researcher Professor Gary Wenk said: ‘When we’re young, we produce neurons and our memory works fine.

‘When we age, the process slows down, so we have a decrease in new cell formation through normal ageing.

‘You need these cells to come back and help form new memories and we found that this THC-like agent can influence the creation of these cells.’

Although the drug used was not suitable for use in people, the results could aid the creation of new medicines for Alzheimer’s.

It is likely such a drug would be taken to prevent the disease, rather than treat it.

Asked if those with a family history of Alzheimer’s should smoke cannabis to prevent them developing the disease, Dr Wenk said: ‘We’re not saying that but it might actually work.

‘What we are saying its that it appears that a safe, legal substance that mimics the important properties of marijuana can work on the brain to prevent memory impairments in ageing.  So that’s really hopeful.’

Dr Marchalant added: ‘We hope a compound can be found that can target both inflammation and neurogenesis, which would be the most efficient way to produce the best effects.’

The medicinal properties of cannabis have already been harnessed to treat multiple sclerosis.

Sativex, a cannabis-based drug, has been shown to ease the symptoms of multiple sclerosis, including pain, spasms, shaking, depression and anxiety.

The Alzheimer’s Society cautioned against using cannabis itself to stave off dementia.

Professor Clive Ballard, the charity’s director of research, said: ‘There are encouraging findings from studies with animals suggesting that some cannabis derivatives may help protect nerve cells in the brain.

‘We therefore look forward to robust clinical trials into potential benefits of non-psychoactive components of cannabis.

‘It is important for people to note that these treatments are not same as recreational cannabis use which can be potentially harmful.

Published by Associated Newspapers Ltd

Part of the Daily Mail, The Mail on Sunday & Metro Media Group

Read more: http://www.dailymail.co.uk/health/article-1087544/Cannabis-stop-dementia-tracks.html#ixzz1gHp3Kv8U

Banking Problems Could Kill Medical Marijuana In Colorado

By | Colorado Medical Marijuana Law, General Medical Marijuana Information, Medical Marijuana Law, News | No Comments

By Steve Elliott

Colorado medical marijuana business owners are desperately writing letters to every bank in the country asking if they can please, oh please, just have a bank account.

About 150 dispensary owners across the state are looking for banks that will take their accounts, said Tanya Garduno, president of the Colorado Springs Medical Cannabis Council and owner of Medical Cannabis Center, reports Monica Mendoza at InsuranceNewsNet.
The medical marijuana industry has already survived regulations, licensing, security and thick stacks of almost impenetrable rules and legalese.

But the banking issue “could be the deal breaker,” Garduno said. “We have to account for everything — sales, patient lists — trying to put this together with no bank could really kill us.”

The last bank in Colorado to openly welcome dispensaries’ business — the Colorado Springs State Bank — sent notice to the shops almost two months ago that they had until the end of September to clear out their accounts. That ban is owned by parent company Herring Bank, based in Texas.
“Everyone is trying to make it work on a cash basis,” Garduno said. “It’s going to be a funky next three months. I’m sure there will be folks that will shut down.”
Medical marijuana businesses in Colorado Springs have generated about $23 million in sales and contributed $580,533 in sales taxes so far this year. That’s a 52 percent increase over last year’s numbers, and a sign that the industry continues to grow.
But most bankers won’t touch medical marijuana dispensaries with a 10-foot pole.
Banks fear federal charges of money laundering and drug trafficking. While use and sale of medical marijuana are legal in Colorado, the federal government does not recognize any legal use for cannabis.
The Federal Deposit Insurance Corporation (FDIC), one of three banking regulators, hasn’t issued guidance for banks doing business with medical marijuana dispensaries. But federal law does require banks to report “suspicious activity.”
And in June, U.S. Deputy Attorney General James Cole issued a memo to U.S. Attorneys in medical marijuana states saying “Persons who are in the business of cultivating, selling or distributing marijuana, and those who knowingly facilitate such activities, are in violation of the Controlled Substances Act, regardless of state law.”
Colorado dispensary owners are planning to fight.
They plan to push for changes in federal law to take marijuana off Schedule I, which officially means it has no accepted medical uses, a high potential for abuse and addiction, and is too dangerous to use even under medical supervision — you know, like heroin. (Even cocaine and methamphetamine are considered by the U.S. federal government to be Schedule II drugs — officially “less dangerous” than marijuana.)
The dispensary owners and supporters want changes in banking rules that would allow banks to work with medical marijuana businesses without fear of conflicting with federal regulations.
And when the Colorado Legislature goes into session in January, they will push for a change in state law that would allow them to open their own bank, one that does not require federal insurance.
“There is a slight chance they will pass,” Black said. “But, I think we are knocking at the door.”
Without bank accounts, dispensary owners don’t have access to ATM machines and are paying bills in cash or are buying prepaid credit cards.
The dispensaries will be begging for a bank until federal laws change, according to Garduno.
“We need to cut off the short term bleeding,” Garduno said. “We will call every bank in the country to find a bank to give us a shot.”

Medical Marijuana Update

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So much is going on in the world of medical marijuana that we cannot adequately cover it all through news briefs and the occasional feature article. The news briefs and feature articles will, of course, continue, but beginning now, we will also include a weekly medical marijuana update at least noting all those stories we are unable to cover more comprehensively. This first update will itself be updated until the next Drug War Chronicle is published on Thursday, then the updates will appear as a regular weekly feature. Here we go:

National

On Wednesday, the governors of two medical marijuana states, Christine Gregoire (D) of Washington and Lincoln Chafee (I) of Rhode Island, called on the Obama administration to reschedule marijuana. The next day, Vermont Gov. Peter Shumlin (D) said he would join them, but that same day, Nevada Gov. Brian Sandoval (R) said he would not.

California

As of the end of November, the US Attorney’s Office in San Diego reportedthat more than 60% of the 222 dispensaries in the region have closed their doors since it began sending threat letters in October to the outlets and their landlords. That’s 139 dispensaries gone in far Southern California, and the feds said they expected another 20 or so to close in the next two weeks.

On Monday, a federal judge in San Francisco declined to issue a temporary injunction blocking a federal crackdown on dispensaries in the Bay Area. US Attorney Melinda Haag had ordered those clubs to close, because they were too close to schools on parks. Two of the targeted dispensaries, San Francisco’s Divinity Tree and Medithrive, have already shut down to avoid criminal prosecution or seizure of their properties. A third, the Marin Alliance for Medical Marijuana in Fairfax, may be about to follow (see below).

Also on Monday, the last dispensary in the Stockton area shut down after receiving one of those October threat letters from federal prosecutors. County officials had banned dispensaries. One other dispensary shut down in October, and two more are on hold as city officials await clarification from state and federal authorities.

Also on Monday, the city of Novato voted to renew its expiring moratorium on dispensaries for another year and said city staffers would move to shut down two dispensaries operating in violation of city zoning ordinances. The moratorium does not apply to the two dispensaries because they were grandfathered in, but staffers said they are prohibited under city zoning rules, which do not name marijuana sales as an allowed use.

Also on Monday, the Amador County Board of Supervisors temporarily banned outdoor medical marijuana grows in the wake of a September killing during the attempted robbery of a medical marijuana grow. A task force drafting regulations for outdoor grows will meet later this month. Amador County Counsel Gregory Gillott said Fresno, El Dorado, Glenn and Lassen counties all have similar bans on outdoor growing.

A Marin County judge Friday declined to quash an eviction order aimed at closing the Marin Alliance for Medical Marijuana dispensary in Fairfax. The Marin Alliance is the longest operating dispensary in the state, but it could be doomed after being targeted by federal prosecutors in October. Founder and operator Lynette Shaw has until December 9 to answer the ruling and request a trial, but said this week she wasn’t sure she will stay open.

Also on Friday, the Orange County Sheriff’s Department said that any sales of medical marijuana are illegal. After raids last month that targeted a half-dozen dispensaries and more than a dozen other locations and persons, the department said Proposition 19 and laws passed to regulate medical marijuana in the state “do not authorize sales of marijuana.”

Also on Friday, Los Angeles City Attorney Carmen Trutanich announced that his office is targeting nine dispensaries to be shut down because they’re within 600 feet of a school. He said he would seek $2,500 a day penalties if they stay open while being sued. Meanwhile the city reports that 372 marijuana businesses had filed to begin paying a city business tax by the October 31 deadline. An unknown number had not filed, but city officials said there could be as many as 500 dispensaries in the city, down from a peak of 850.

Massachusetts

The Committee for Compassionate Medicine, which is seeking to put a medical marijuana initiative on the ballot next year, announced Friday that it had had handed in more than 74,000 signatures and planned on handing in another 10,000 by next week’s deadline. They need 68,911 valid voter signatures to make the ballot, so even if they get that additional 10,000, it’s still going to be a very close call, given that some sizeable fraction of signatures gathered will be found to be invalid.

Michigan

An Oakland County circuit court judge Wednesday threw out a lawsuit filed by the ACLU and two medical marijuana patients against the cities of Birmingham and Bloomfield Hills, which had passed ordinances saying it is unlawful for anyone to engage in an activity contrary to state, local, or federal law. The judge dismissed the suit, saying the plaintiffs had not been charged with any crimes. The ACLU and the plaintiffs had hoped to force a ruling on whether state and local law enforcement had to obey the Michigan Medical Marijuana Act, but they didn’t get it.

On Thursday, two Oakland County dispensaries were raided by the Oakland County Narcotics Enforcement Team. Police arrested three people at one dispensary and four at the other and seized a combined five pounds of medical marijuana and three pounds of edibles. No charges have been filed yet.

New Jersey

A Rutgers-Eagleton poll released November 30 found overwhelming Garden State support for medical marijuana and high levels of support for marijuana law reform as well. A whopping 86% of respondents supported the availability of medical marijuana, while 60% thought penalties for pot use should be relaxed, just over half didn’t think pot possession should not be a crime, and one-third would completely legalize its sale and use.
 

The poll was released just a day after Gov. Chris Christie (R) announced that he had appointed a law enforcement figure, retired State Police Lt. John O’Brien to oversee the program, which has yet to actually serve a single patient nearly three years after it was passed into law. The first strictly-regulated compassion centers are set to open next year.

The state Department of Health and Human Services last month finally published rules and regulations for the program, which were roundly denounced by the Coalition for Medical Marijuna—New Jersey, the state’s leading patient advocacy group.

Wisconsin

At a Wednesday news conference at the state capitol in Madison, Rep. Mark Pocan (D-Madison) announced that he is introducing  LRB-2466, the Jackie Rickert Medical Marijuana Act (JRMMA), named after the wheelchair-bound patient, activist, and member of Is My Medicine Legal Yet, the state’s most prominent medical marijuana activist group.

Pocan and state Sen. Jon Erpenbach (D-Waunakee) will be the lead sponsors of the bill, which died without a committee vote last session. Activists in Wisconsin have been working for a decade to pass medical marijuana legislation. Whether it will happen this session, given the bitter political atmosphere and Republican nomination at the state house remains to be seen.

MMED to begin investigation of the Mother Earth Medical Marijuana Center

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Denver – October 7, 2011 In the culmination of a joint investigation, the Medical Marijuana Enforcement Division (MMED) partnered with the TRIDENT Two Rivers Drug Enforcement Team to investigate alleged illegal activity taking place at a Medical Marijuana Center in Carbondale, CO.

The MMED began an investigation of the Mother Earth Medical Marijuana Center after receiving information that the Center sold to individuals without the statutorily required documentation and was selling or offering to sell illegal drugs. The MMED contacted the TRIDENT Two Rivers Drug Enforcement Team and in a collaborative effort were able to determine that the Center owner was indeed engaging in illegal activity. The TRIDENT/MMED joint operation yielded evidence of an illegal Medical Marijuana purchase and the sale of suspected cocaine to an undercover officer.

Today, the Center owner has been arrested and the Center and its Cultivation shut down. Further investigation into other individuals that may be involved is ongoing, and additional arrests may be made as a result of this joint operation. All Medical Marijuana has been confiscated by the MMED and the Center/Cultivation application for a State MMED business license has been officially denied. Today is an example of how the MMED provides a valuable resource for other law enforcement agencies by partnering with them to provide both agencies with increased manpower and institutional knowledge to stop illegal activity within Colorado’s Medical Marijuana industry and our state.

Division Director Dan Hartman said “While the MMED is currently working to educate members of the Medical Marijuana industry and bring them into compliance with current statute and rule, we will not hesitate to take immediate action when we are made aware of blatant illegal activity. Due to Colorado’s unambiguous regulatory scheme we were able to identify an industry member that was not operating in compliance with the law and partner with the local authority to take action. It is gratifying to have the opportunity to work with our fellow law enforcement officers to make Colorado’s Medical Marijuana industry a safe place for patients to purchase this medicinal product” – said Hartman. “In this time of limited funding, TRIDENT and the MMED were able to pool their resources to put an end to this illegal drug activity and ensure the integrity of the industry we regulate.”

Today also helps validate the large majority of Medical Marijuana business owners that work hard to operate within our state’s regulatory scheme. These small business owners have spent a great deal of time and money to do so and are directly impacted by businesses not interested in compliance. The MMED will continue to investigate and stop illegal activity within our industry.

The TRIDENT Two Rivers Drug Enforcement Team was established in 1994 and is based in Glenwood Springs. This task force unites participating agencies within Garfield County to directly address illegal drug activity and decrease the amount of illegal drugs available within area served by TRIDENT. Participating agencies include: Carbondale Police Department, Drug Enforcement Administration, Garfield County Sheriff’s Office, Glenwood Springs Police Department, Rifle Police Department, Rocky Mountain High- Intensity Drug Trafficking, Silt Police Department and the Vail Police Department. In order to obtain additional information about TRIDENT visit their web site at http://tridentnarc.com/

The MMED was created through legislation in the 2010 Legislative Session and is tasked with regulation of the commercial Medical Marijuana industry. The agency has been operational since July 1 2010, and is establishing a robust monitoring system for this industry. More information on the MMED may be found on our web site at www.colorado.gov/revenue/medicalmarijuana

Rhode Island scraps Medical Marijuana

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Rhode Island: Governor Lincoln Chafee scrapped the plan for fear it was illegal under federal law. “Federal injunctions, seizures, forfeitures, arrests and prosecutions will only hurt the patients and caregivers that our law was designed to protect,” the governor said in the statement late Thursday (9.29.2011). Rhode Island considered state run facilities called “compassionate centers” but will no longer pursue the plan in fear of federal involvement. Patients and caregivers will still be able to cultivate their own medicine but state run facilities will no longer be an option. There are currently around 2,500 licensed caregivers in the state.

California Medical Marijuana Dispensary Crack Down

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LOS ANGELES (KABC) — Federal prosecutors announced Friday the government would aggressively crack down on California medical marijuana dispensaries.

Federal officials say offenders are using the cover of medical marijuana to sell drugs through storefronts.

Officials are targeting dispensaries located near schools, playgrounds, parks and sports fields where children are likely to congregate.

Arrests and indictments in California have been made in recent days by federal officials.

As part of a coordinated effort by California’s four United States Attorneys, federal prosecutors in Los Angeles have taken a series of actions against illegal commercial marijuana operations, including a building in South Orange County that houses eight marijuana stores and a trafficking ring that sold marijuana at its San Fernando Valley storefront, and sent marijuana to customers as far away as New York state.

The actions announced Friday in the Central District of California include:

    • A criminal indictment that charges six people with marijuana trafficking that allegedly generated nearly $15 million in profits in only eight months
    • The filing of civil forfeiture lawsuits against three properties and a related seizure of more than $135,000 from the bank account of one property owner
    • Warning letters sent to the operators and landlords of 38 marijuana stores.

Haag said the move is not designed to clamp down on patients who grow their own marijuana for medical use. But dispensaries that were not part of the initial wave of warning letters “shouldn’t take any comfort,” she said. “They are illegal under federal law.”

The move comes a little more than two months after the Obama administration toughened its stand on medical marijuana. For two years before that, federal officials had indicated they would not move aggressively against dispensaries in compliance with laws in the 16 states where pot is legal for people with doctors’ recommendations.

According to the U.S. District Attorney’s Office in Los Angeles, all known marijuana stores in the following areas are being sent letters warning that their operations are in violation of federal law:

    • Orange County: Lake Forest, Dana Point, Laguna Hills, Laguna Niguel, and Rancho Santa Margarita
    • Riverside County: Murrieta, Wildomar, Temecula
    • Inland Empire: Pomona, Claremont, Upland, Montclair, Chino

According to a spokesman for the U.S. attorney, at this time no cities in Ventura County are being targeted. But he said this is an initial phase and more locations will likely be added at a later date. warning letters sent to the operators and landlords of 38 marijuana stores.

The Associated Press contributed to this report.

(Copyright ©2011 KABC-TV/DT. All Rights Reserved.)

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